Discovering the Genome is a web-based curriculum for science classes. The curriculum consists of modules that introduce genomics to students.  The modules include videos, activities, discussion questions, and other tools so students can  explore and discover the genome.

Course Module Features

  • Modules are listed on the left in order of foundational topics to more advanced topics.
  • Modules are designed to be self-contained and can be used as a whole or in sections that enhance your existing curriculum.
  • Module descriptions and educator tips are in the For Teachers section of the website.
  • Modules can be used in any order that is appropriate for your students.

Genomics is an exciting, quickly advancing technical field. It affects healthcare, food production, natural resources management, and environmental conservation. It stimulates bioengineering and synthetic biology solutions. It answers questions about biology and life that haven’t answered before. It poses many more new questions. We invite you and your students to discover the genome…

The NAPCore Facility, The Joseph Stokes Jr Research Institute, CHOP

Genomic Tools Facilitate Treatment of Patients

Genome-wide occupancy pattern of TCF7L2, which is a transcription factor known to play a key role in multiple diseases including cancer. The data were generated using a technique called ChIP-seq, which leverages state-of-the-art whole genome sequencing technology. Analyses like these are used to identify key vulnerabilities in disease-related pathways to facilitate better treatment of patients at the Children’s Hospital of Philadelphia. CHOP has facilities such as the Nucleic Acid/Protein Research Core Facility that perform these types of genomic analyses.